Research on oxytocin suggests it may offer neuroprotection against Huntington's disease-like damage. Rabie et al. (2025) Oxytocin appears to have anti-apoptotic properties, helping prevent the programmed death of nerve cells. This is partly due to its interaction with pathways involving calpain-2, a protein that promotes cell death.
By reducing the harmful activity of calpain-2 and supporting cell survival, oxytocin could help slow down or mitigate brain damage in Huntington's disease. This finding suggests a potential therapeutic avenue for the disease, which typically involves worsening symptoms over time. The protective effects of oxytocin highlight its potential as a treatment option, although more research is needed to fully understand its benefits.
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